Ethan Nadelmann, one of the leading drug reformers in the United States, had explained: “People overdose because [under prohibition] they don’t know if the heroin is 1 percent or 40 percent…Just imagine if every time you picked up a bottle of wine, you didn’t know whether it was 8 percent alcohol or 80 percent alcohol [or] if every time you took an aspirin, you didn’t know if it was 5 milligrams or 500 milligrams.